The importance of biodiversity and the severity of current losses are well-recognized. Land-use change for agricultural expansion is one of the main drivers of biodiversity declines. Agricultural expansion has largely served global commodity supply chains. Increasing awareness and commitment to address the environmental impacts of these commodity supply chains has been shown in recent years. To address this, our analytical tools present state-of-the-art and spatially explicit quantification of biodiversity patterns at regional to continental scales using satellite earth observation. Such information can help inform, guide, and reshape supply chain management regarding biodiversity losses caused by agricultural expansion and sourcing decisions, weighing in on the impact of agricultural commodities on plant biodiversity in (expanding) production landscapes.